Niclosamide Bolus 1250 MG
Niclosamide Bolus yana hana phosphorylation a cikin mitochondria na cestodes. A cikin vitro da kuma a cikin jiki, sassan scolex da proximal suna mutuwa idan aka taɓa maganin. Scolex da aka sassauta zai iya narkewa a cikin hanji; saboda haka, yana iya zama ba zai yiwu a gano scolex a cikin najasa ba. Niclosamide Bolus yana kashe ƙwayoyin cuta a cikin aiki kuma yana kawar da ƙwayoyin cuta ba kawai ba har ma da scolex.
Ayyukan Niclosamide Bolus akan tsutsotsi ya bayyana ne saboda hana mitochondrial oxidative phosphorylation; samar da anaerobic ATP shima yana shafar.
Aikin cestocidal na Niclosamide Bolus ya faru ne saboda hana shan glucose ta hanyar tsutsar tapeworm da kuma cire haɗin oxidative phosphorylation a cikin mitochondria na cestodes. Tarin lactic acid wanda ya samo asali daga toshewar zagayowar Krebs yana kashe tsutsotsi.
Alamomi
Ana nuna Nicosamide Bolus a cikin kamuwa da tsutsotsi na dabbobi, kaji, karnuka da kuliyoyi, da kuma a cikin paramphistomiasis (Amphistomiasis) na shanu, tumaki da akuya.
Tsutsotsi masu tapeworm
Shanu, Awaki da Barewa: Nau'in Moniezia Thysanosoma (Tsutsotsi masu laushi)
KarnukaDipylidium Caninum, Taenia Pisiformis T. hydatigena da T. taeniaeformis.
Dawakai: Cututtukan Anoplocephalid
Kaji: Railletina da Davainea
Amphistomiasis: (Masu Alaƙa Marasa Girma)
A shanu da tumaki, cutar Rumen flukes (nau'in Paramphistomum) ta zama ruwan dare gama gari. Yayin da cutar manya da aka haɗa a bangon rumen ba ta da wani tasiri, waɗanda ba su kai ba suna da matuƙar illa ga lafiya, suna haifar da mummunar lalacewa da mace-mace yayin da suke ƙaura a bangon duodenal.
Ya kamata a yi zargin cewa dabbobin da ke nuna alamun rashin isasshen abinci mai gina jiki, yawan shan ruwa, da gudawa mai yawa a cikin fitsari suna da cutar amphistomiasis kuma a yi musu magani nan da nan da Niclosamide Bolus don hana mutuwa da asarar haihuwa tunda Niclosamide Bolus yana da tasiri sosai akan mura masu ƙarancin shekaru.
Tsarin aiki
Kowane bolus ɗin da ba a rufe shi ba ya ƙunshi:
Niclosamide IP 1.0 gm
Gudanarwa da sashi
Niclosamide Bolus a cikin abinci ko kamar haka.
Akan tsutsotsi masu tafe
Shanu, Tumaki da Dawakai: gram 1 na bolus ga nauyin jiki kilogiram 20
Karnuka da Kuraye: gram 1 na bolus ga nauyin jiki kilogiram 10
Kaji: gram 1 na bolus ga tsuntsaye 5 manya
(Kimanin 175 MG a kowace kg nauyin jiki)
A kan Amphistomes
Shanu da Tumaki:Mafi girman allurai a cikin adadin gram 1.0 na bolus / kilogiram 10 na nauyin jiki.
Tsaro:Niclosamide bolus yana da fa'ida sosai a fannin aminci. An gano cewa yawan shan Niclosamide har sau 40 a cikin tumaki da shanu ba shi da guba. A cikin karnuka da kuliyoyi, sau biyu na maganin da aka ba da shawarar ba ya haifar da wata illa sai dai laushin najasa. Ana iya amfani da Niclosamide bolus lafiya a kowane mataki na ciki da kuma ga waɗanda suka ji rauni ba tare da wata illa ba.
